Kerstin Danker, Evotec, Hamburg

Since almost five years Evotec offers High Throughput Mass Spectrometry (HTMS) screening services for label-free hit identification programs. In this presentation we present how the Agilent RapidFireTM (RF) technology has been fully integrated into Evotec’s Lead Discovery Platform and give examples for the analysis of small and polar molecules in a much more efficient way in comparison to traditional HPLC- or UPLC-coupled mass spectrometry approaches. In this context we also outline the accessibility of biological assay systems which are not commonly investigated by other label-free detection methods.