"Targeted Protein Degradation"

08:00

08:20

Registration

   

08:20

08:30

Welcome by the Chairman of ELRIG.de e.V.

Tobias May

Elrig.de e.V.

08:30

09:00

Clues to Molecular Glues

Felix Hausch

TU Darmstadt-Structure-Based Drug Research

09:00

09:30

Characterisation of glue degrader ternary complex dynamics and their effect on target degradation

Grasilda Zenkeviciute

Proxygen, Wien

09:30

10:00

Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization

Martin Schwalm

Inst. f. Biochemie, Goethe Uni Frankfurt

10:00

10:30

Licence to eliminate – degraders at Merck

Carola Sparn

Merck KGaA, Darmstadt

10:30

11:00

Coffee break & Postersession

   

11:00

11:30

Deep proteomic screening for systematic discovery of degrader targets and mechanisms

Henrik Daub

NEOsphere, München

11:30

12:00

A novel E3-ligase-dependent glue degrader targeting STING

Benedikt Goretzki

Novartis, Basel

12:00

13:45

Lunch Break & Poster Session

   

13:45

14:15

Measurement of PROTAC ternary complex formation using the switchSENSE® Y-structure and FRET signals

Ralf Strasser

Dynamic Biosensors GmbH, München

14:15

14:45

Applying a „first principle“ biophysical method for Targeted Protein degradation

Hedeby Hasse

Fida Biosystems, Herlev, Dänemark

14:45

15:15

Mass photometry – an analytical technology for biomolecular characterization

Jan Schäferkordt

Refeyn Ltd. Oxford, UK

15:15

15:45

PRISKA: Integrated screening- and knowledge-platform for molecular degrader discovery

Johanna Huchting

ITMP Fraunhofer Hamburg

15:45

16:15

Enabling effective data management for PROTAC development

Emilia Hietala

Collaborative Drug Design, UK

16:15

16:45

Coffee break & Postersession

   

16:45

17:15

Deconvoluting the drivers of targeted protein degradation

Kristin Riching

Promega, USA

17:15

17:25

Snapshot: Simple Western with Jess is even more simple with CyBio FeliX Liquid Handling

Christoph Heddergott

Analytik Jena GmbH, Jena

17:25

17:30

Wrap up Forum 2023

Axel Johann

Promega, Walldorf